Gynaecology Drugs for franchise

Product Details:

Brand Name-ALNAGEST-200 SOFTGEL CAPSULES

Composition- Micronised Progesterone 200 mg softgels

Packing-10*10 Blister pack softgels


Brand Name-ALNAGEST-200 INJECTION

Composition- Natural Progesterone 200 mg 

Packing- 2ml DISPO PACK
MRP-175/DISPO PACK

WHAT IS PROGESTERONE?

•         Essential hormone, plays important role in women’s reproductive cycle.

•         Name derived from “progestational steroid hormone” – helps to prepare and maintain uterine bed for conception.

•         Secreted by: ovaries, placenta & adrenal glands-essential during luteal phase to sustain pregnancy

•         Antiproliferative endometrial action-  shedding of endometrium-maintain regular menstrual cycle.

•         VARIOUS ROLES OF PROGESTERONE

•         transition of the endometrium from the proliferative to the secretory phase   

•         preparation of the endometrium for potential implantation 

•         maintaining pregnancy 

•         the reduction of uterine muscular activity through the development of increased numbers of β-adrenergic receptors and the reduction of sensitivity to oxytocin 

•         the reduction of prostaglandin synthesis 

•         stimulating the development of lobuli and mammary ducts in breast tissue  

•         High levels of progesterone during pregnancy serve to prepare the mammary glands for lactation 

Indications-

• Preterm delivery
• Threatened abortion
• hormone replacement therapy with strogen
• Assisted reproductive technology (ART cycle)
• Embryo implantation
• Menstrual irregularities

Additional Information:

• Packaging Details: 10*10 blister

Product Details:

BRAND NAME-PREGAMASH-L TABLETS 

COMPOSITION- LEVONORGESTREL IP 0.15 MG + ETHINYLOESTRADIOL IP 0.03 MG 

PACKING-12*1*21 TABLETS BLISTER PACK

•          

LEVONORGESTREL

Ø Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.

Ø levonorgestrel is the most commonly used emergency contraceptive.

Ø It has high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens.

Ø it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD.

Ø levonorgestrel is used as a component of long-term combination contraceptives.

 

ETHINYLESTRADIOL

•         Ethinyl Estradiol is a semisynthetic estrogen.

•         It was developed in an effort to create an estrogen with greater oral bioavailability. 

q Ethinylestradiol is combined with other drugs for use as a:

ü Contraceptive

ü  premenstrual dysphoric disorder

ü  moderate acne

ü  moderate to severe vasomotor symptoms of menopause

ü  prevention of postmenopausal osteoporosis.

BENEFITS OF PREGAMASH-L TAB OVER OTHER CONTRACEPTIVES

•         ultra-low-dose oral contraceptive product.

•         Very good cycle regulation.

•         an acceptably low rate of intermenstrual bleeding.

•         no major side effects.

•         effective contraception with a very low incidence of side effects.

INDICATIONS:

PREVENTION OF PREGNANCY 

Additional Information:

• Packaging Details: 12*1*21 TABLETS

Product Details:

brand name-femiwise-35 tablets

composition-cyproterone acetate 2mg + ethinylestradiol 0. 035 mg tab

packing-10*2*21 tablets blister pack

•       CYPROTERONE ACETATE

•      Cyproterone Acetate is the acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities.

•       It suppresses the actions of testosterone (and its metabolite dihydrotestosterone) on tissues. It acts by blocking androgen receptors which prevents androgens from binding to them and suppresses luteinizing hormone (which in turn reduces testosterone levels)

•      It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.

•      Ethinylestradiol

•      Ethinyl Estradiol is a semisynthetic estrogen.

•      It was developed in an effort to create an estrogen with greater oral bioavailability. 

•      Ethinylestradiol is combined with other drugs for use as a:

•      Contraceptive

•       premenstrual dysphoric disorder

•       moderate acne

•       moderate to severe vasomotor symptoms of menopause

•       prevention of postmenopausal osteoporosis.

•      INDICATIONS OF FEMIWISE-35 TABLETS

•      1) ANDROGEN DEPENDENT ALOPECIA

•      Androgenetic alopecia (AGA) is hereditary and androgen-dependent, progressive thinning of the scalp hair that follows a defined pattern.

•      2) HIRSUTISM 

•      Hirsutism  is a condition in women that results in excessive growth of dark or coarse hair in a male-like pattern — face, chest and back.

•      With hirsutism, extra hair growth often arises from excess male hormones (androgens), primarily testosterone

•      3) ANDROGEN DEPENDENT ACNE.

•      ACCOMPANIED BY SEBORRHOEA OR FORMATION OF INFLAMED NODES

•      4) ORAL CONTRACEPTION IN WOMEN REQUIRING ANTOANDROGEN THERAPY

Additional Information:

• Packaging Details: 10*2*21 tablets blister pack

Product Details:

BRAND NAME-ALNAMET-OVA TABLETS

COMPOSITION-Myo-Inositol (550mg) + D-Chiro Inositol (13.8mg) + Metformin (500mg) + L-Methyl Folate Calcium (0.5mg) + Methylcobalamin (750mcg) 

PACKING-10*10 STRIP PACKING TABLETS 

•        MYO-INOSITOL

• . It is the precursor of inositol triphosphate, acting as an intracellular second messenger and regulating a number of hormones such as thyroid-stimulating hormone, follicle-stimulating hormone (FSH) and insulin.

•       Many hormonal and reproductive impairments associated with this disorder seem relieved by the supplement.

•      Myo-inositol modulates the activation of glucose transporters and glucose utilization, and glycogen synthesis takes place under the control of d-chiro-inositol (DCI). This molecule on the ovary regulates the insulin-induced androgen synthesis, whereas MI regulates glucose uptake and FSH signaling .

•      MI has been used to prevent and/or treat a number of metabolic disorders related to insulin resistance, such as the metabolic syndrome , gestational diabetes mellitus and the polycystic ovary syndrome (PCOS).

•      D-CHIRO INOSITOL

•     In lean women with the polycystic ovary syndrome, D-chiro-inositol reduces circulating insulin, decreases serum androgens, and ameliorates some of the metabolic abnormalities (increased blood pressure and hypertriglyceridemia) of syndrome X.

•      METFORMIN

•      Polycystic ovary syndrome (PCOS) is an endocrinopathy characterised by increased resistance to insulin.

•      Metformin is one of the longest established oral insulin sensitising agents.

• its properties as an insulin sensitising agent have been explored in relation to its applicability for women with PCOS.

•      Metformin is an effective ovulation induction agent for non-obese women with PCOS and offers some advantages over other first line treatments for anovulatory infertility such as clomiphene.

•       •      INDICATIONS 

 

•      1.Female Infertility.

•      2. Menstrual Irregularities

•      3. Management of PCOS:

•      Women with Polycystic ovarian syndrome (PCOS) have hormonal imbalance that is responsible for irregular menstrual cycles (periods), excessive hair growth and acne.

•      Alnamet-Ova Tablet is a combination medicine that helps in regulating hormonal imbalance as well as periods in females.

•       It helps the body to utilise the hormone insulin and also regulates menstrual cycles. Take it as prescribed by the doctor.

 

Product Details:

BRAND NAME-ALNAGEST 300 SR TABLETS 

COMPOSITION-NATURAL PROGESTERONE 300 MG

PACKING-10*1*10 ALU-ALU PACKING 

•         WHAT IS PROGESTERONE?

•         Essential hormone, plays important role in women’s reproductive cycle.

•         Name derived from “progestational steroid hormone” – helps to prepare and maintain uterine bed for conception.

•         Secreted by: ovaries, placenta & adrenal glands-essential during luteal phase to sustain pregnancy

•         Antiproliferative endometrial action-  shedding of endometrium-maintain regular menstrual cycle.

•         VARIOUS ROLES OF PROGESTERONE

•         transition of the endometrium from the proliferative to the secretory phase   

•         preparation of the endometrium for potential implantation 

•         maintaining pregnancy 

•         the reduction of uterine muscular activity through the development of increased numbers of β-adrenergic receptors and the reduction of sensitivity to oxytocin 

•         the reduction of prostaglandin synthesis 

•         stimulating the development of lobuli and mammary ducts in breast tissue  

•         High levels of progesterone during pregnancy serve to prepare the mammary glands for lactation 

Product Details:

BRAND NAME-ALNAGEST 100 SOFTGELS

COMPOSITION-NATURAL PROGESTERONE 100 MG

PACKING-10*10 ALU-ALU PACKING 


BRAND NAME- ALNAGEST-100 INJECTION

COMPOSITION- NATURAL PROGESTERONE 100 MG

PACKING-2 ML DISPO PACK

MRP-99/DISPO PACK

•         WHAT IS PROGESTERONE?

•         Essential hormone, plays important role in women’s reproductive cycle.

•         Name derived from “progestational steroid hormone” – helps to prepare and maintain uterine bed for conception.

•         Secreted by: ovaries, placenta & adrenal glands-essential during luteal phase to sustain pregnancy

•         Antiproliferative endometrial action-  shedding of endometrium-maintain regular menstrual cycle.

•         VARIOUS ROLES OF PROGESTERONE

•         transition of the endometrium from the proliferative to the secretory phase   

•         preparation of the endometrium for potential implantation 

•         maintaining pregnancy 

•         the reduction of uterine muscular activity through the development of increased numbers of β-adrenergic receptors and the reduction of sensitivity to oxytocin 

•         the reduction of prostaglandin synthesis 

•         stimulating the development of lobuli and mammary ducts in breast tissue  

•         High levels of progesterone during pregnancy serve to prepare the mammary glands for lactation 

Additional Information:

• Packaging Details: 10*10 blister

Product Details:

BRAND NAME: UTZIL SYRUP
CPMPOSITION: CRANBERRY EXTRACT 200MG+ D-MANNOSE 300 MG,POTASSIUM MAGNESIUM CITRATE 978MG SYRUP
PACKING: 220 ML
MRP: 290/-

DESCRIPTION:
 
 A. CRANBERRY EXTRACT:
1. WORKS FOR URINARY TRACT INFECTIONS BY MAKING THE URINE ACIDIC& HENCE STOPS THE GROWTH OF BACTERIA.
2. USED FOR KIDNEY STONES,TO DEODORIZE URINE IN PEOPLE WITH DIFFICULTY CONTROLLING URINTION,NEURGENIC BLADDER, TO PREVENT URINE CATHETERS FROM BECOMING BLOCKED.
3. USED TO INCREASE URINE FLOW,AND KILL MICROBES.

B. D-MANNOSE:
1. INHIBITS THE P-FIMBREAL ADHESION OF E-COLI TO THE URINARY BLADDER,THUS PREVENTS REOCCURRENCE.
2. DUAL SUPPORTS FOR URINARY TRACT COMFORT,ENHANCES URINARY TRACT FUNCTIONALITY.

C. POTASSIUM MAGNESIUM CITRATE:
1. DECREASES THE ACIDITY OF URINE AND HELPS THE KIDNEYS TO GET RID OF URIC ACID, THEREBY PREVENTING GOUT AND KIDNEY STONES.
2. USFDA APPROVED SPECFIC URINARY ALKALISER.

INDICATION: 
1. URINARY TRACT INFECTION.
2. BACTERIURIA.
3. UTIS DURING PRAGNANCY.
4. KIDNEY STONE,RENAL CALCULI.

Product Details:

 BRAND NAME – VULVOFEN SOFTGELS

COMPOSITION- FENTICONAZOLE 600 MG

PACKING- 1*30 BLISTER PACK SOFTGELS

Composition : Fenticonazole 600 mg

Pharmacotherapeutic group : broad-spectrum imidazole antimycotic agent with high fungistatic and fungicidal activity against dermatophytes (all species of Trichophyton, Microsporum, Epidermophyton), Candida albicans and other mycotic agents of the skin and the mucosa.

Also have antibacterial activity against Gram positive bacteria and an antiparasitic action against Trichomonas vaginalis.

•      MECHANISM OF ACTION-

Fenticonazole shows unique multimodal action against Candida species involving:

 1. Inhibition of secretary aspartate protenase (SAP) there by preventing the growth, adherence,and penetration of Candida sp.

•      2. Inhibits fungal cytochrome P450 3A enzyme, lanosine 14α-demethylase responsible for conversion of lanosterol to ergosterol, the main sterol attributed to fungal cell membrane integrity and cell survival.

•      3. Inhibits complimentary oxidase and peroxidase enzymes that lead to structural and functional changes in fungal cell due to its antioxidant action.

•      Similarly, fenticonazole inhibits the growth of bacterial (Gardenella vaginalis) and Protozoan (Trichomonas sp.) by inhibition of pyruvate oxido reductase enzyme responsible for cell division or replication.

•      Indications:

•      1) Vulvovaginal Candiasis.

•      2) Vaginal thrush: Most cases of thrush are caused by the yeast called Candida albicans but other types of Candida spp. can also cause thrush.

•       Common symptoms of vaginal thrush are itching, soreness, and redness around the outside of the vagina and a thick, creamy white, odourless vaginal discharge. 

•      Why fenticonazole?

•      Fenticonazole has also been shown to exhibit antibacterial action, with a spectrum of activity that includes bacteria commonly associated with superinfected fungal skin and vaginal infections, and antiparasitic action against the protozoan Trichomonas vaginalis.

•      It is an ideal topical alternative to multi-agent treatment of mixed infections involving mycotic, bacterial, dermatophyte and/or Trichomonas spp.

•      very well tolerated, with no reports of appreciable local or systemic adverse reactions.

•      short course therapy benefits that can be safely given to high-risk patients including pregnancy albeit from second trimester onward.

•      POSOLOGY:
One 600 mg soft vaginal capsule should be inserted deeply into the vagina at bedtime. A second administration can be repeated after three days if symptoms persists

Additional Information:

• Packaging Details: 1*30 capsules blister pack

Product Details:

BRAND NEME- ALNAGEST-200 SR TABLETS

COMPOSITION-NATURAL PROGESTERONE 200MG SUSTAIN RELEASED

PACKING-10*10 ALU-ALU PACKING TABLETS

WHAT IS PROGESTERONE?

•         Essential hormone, plays important role in women’s reproductive cycle.

•         Name derived from “progestational steroid hormone” – helps to prepare and maintain uterine bed for conception.

•         Secreted by: ovaries, placenta & adrenal glands-essential during luteal phase to sustain pregnancy

•         Antiproliferative endometrial action-  shedding of endometrium-maintain regular menstrual cycle.

•         VARIOUS ROLES OF PROGESTERONE

•         transition of the endometrium from the proliferative to the secretory phase   

•         preparation of the endometrium for potential implantation 

•         maintaining pregnancy 

•         the reduction of uterine muscular activity through the development of increased numbers of β-adrenergic receptors and the reduction of sensitivity to oxytocin 

•         the reduction of prostaglandin synthesis 

•         stimulating the development of lobuli and mammary ducts in breast tissue  

•         High levels of progesterone during pregnancy serve to prepare the mammary glands for lactation 

INDICATIONS*
1)  Preterm Delivery
2)  Threatened Abortion
3)  Menstrual Irregularities
4)  Embryo Implantation
5)   Endometrial Hyperplasia

Additional Information:

• Packaging Details: 10*10 ALU-ALU PACK

Product Details:

 BRAND NAME-ALNAMET-MYO TABLETS

 COMPOSITION: METFORMIN 500 SR + MYO INOSITOL  600MG

 

PACKING-10*10 Blister packing

METFORMIN

 

•          Metformin, a time-tested drug for PCOS.

•           It acts by suppressing hepatic gluconeogenesis.

•           It also increases insulin sensitivity, enhances peripheral glucose uptake, and decreases insulin induced suppression of peripheral fatty acid oxidation.

 MYO-INOSITOL

•          Myoinositol is an upcoming drug in the management of PCOS.

•           A deficiency of inositols has been postulated as a key factor in the pathogenesis of PCOS.

•           An increased excretion of inositol in urine has also been observed in patients of PCOS thus leading to its deficiency.

•           Based on these findings, inositols were used for the management of PCOS.

•          Inositols (6 carbon polyols) are second messengers which are responsible for glucose transport intracellularly.

•          It also increases the translocation of GLUT 4 to the cell membrane.

•           At ovarian level, it has been observed that myoinositol based second messenger is involved in both glucose uptake and FSH signalling.

•           Various studies have found a success ranging from 22 to 88% in the management of PCOS.

•          Though the side effects are minimal, the cost of treatment with 2-4g/day for 3-6 months duration, is one of the major constraints.

BENEFIT OF COMBINATION

•          It has been postulated that both the drugs in combination may have additive effect in management of hyperinsulinemia in PCOS with the reduction in the doses of individual drug to achieve similar efficacy.

 

•          Indications of Alnamet-Myo Tab

•          1. PCOS

•          2. INFERTILITY (Due to PCOS)

•          Polycystic ovarian syndrome (PCOS) also known as hyperandrogenic anovulation syndrome or Stein- Leventhal syndrome is an endocrine disorder, characterized by anovulation (lack of ovulation), oligomenorrhea (infrequent periods.),, amenorrhea (absence of menstruation),features of androgenic hormone excess (hirsutism, acne, alopecia, seborrhea) and insulin resistance. Global prevalence ranges from 2.2% to 26%.

Product Details:

 BRAND NAME-DUDOT-M TABLETS

COMPOSITION- DROTAVERINE HCI 80MG +MEFENAMIC ACID 250 MG

PACKING- 10*10 BLISTER TABLETS

DROTAVERINE
.*Drotaverine is an antispasmodic drug with a relaxing effect on smooth muscles.

*structurally related to papaverine, although it displays more potent antispasmodic activities than papaverine.

*INDICATIONS ARE:

 used to alleviate gastrointestinal and genitourinary smooth muscle     spasms, such as cholecystitis (inflammation of the gall bladder) and gallbladder disorders.

•      MECHANISM :
Drotaverine is a selective inhibitor of phosphodiesterase 4 (PDE4), which is an enzyme responsible for the degradation of cyclic adenosine monophosphate (cAMP). Inhibition of PDE4 leads to elevated levels of cAMP, leading to smooth muscle relaxation.

•      MEFENAMIC ACID

•      Mefenamic acid is an NSAID used to treat mild to moderate pain for no more than a week.

•      It is used for the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to
 moderate pain, inflammation, and fever.

•      Mechanism of Mefenamic acid

•      Mefenamic acid binds the prostaglandin synthetase receptors COX-1 and COX-2, inhibiting the action of prostaglandin synthetase.

•      As these receptors have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity, the symptoms of pain are temporarily reduced.

•      Mefenamic acid binds the prostaglandin synthetase receptors COX-1 and COX-2, inhibiting the action of prostaglandin synthetase.

•      As these receptors have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity, the symptoms of pain are temporarily reduced.

•      INDICATIONS OF DUDOT-M TABLETS

•      Abdominal pain

•       Muscle pain

•       Migraine headache

•       Functional bowel disorders

•       Dysmenorrhea (menstrual cramps)

•       Heavy bleeding during periods

•       Renal colic pain

•      Post surgical uterine spasm.

•      Spasmodic pain of any other origin.

Additional Information:

• Packaging Details: BLISTER PACKAGING

Product Details:

BRAND NAME- RAUF-E TABLETS

COMPOSITION- TRANEXAMIC ACID 250 MG + ETAMSYLATE  250 MG TAB

PACKING-10*10 BLISTER TABLETS

TRANEXAMIC ACID

v  Tranexamic acid is one of the most commonly used and widely researched antifibrinolytic agents.

v  A type of drug that helps the blood clot. It prevents the breakdown of a protein called fibrin, which is the main protein in a blood clot.

v   Antifibrinolytic agents may be used to help prevent or treat serious bleeding in patients who have certain conditions, such as hemophilia, very heavy menstrual bleeding, or some types of vascular tumors. They may also be used to help prevent or control bleeding during or after surgery or after a traumatic injury.

 

VARIOUS ROLES OF TRANEXAMIC ACID

1)       Postpartum hemorrhage: is when a woman has heavy bleeding after giving birth. 

 

2) Menorrhagia: menstrual bleeding that lasts more than 7 days. It can also be bleeding that is very heavy.

 

3) Trauma-associated hemorrhage

4) Surgical bleeding

ETAMSYLATE

•          Etamsylate is a hemostatic agent that acts by restoring capillary resistance and improving platelet adhesion.

•          Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface.

 

INDICATIONS OF RAUF-E TABLETS

•          1) Dysfunctional uterine bleeding:

•          Dysfunctional uterine bleeding, also called anovulatory bleeding, is any bleeding from the vagina that varies from a woman's normal menstrual cycle. The normal cycle is triggered by signals from hormones. Dysfunctional uterine bleeding occurs when the cycle's hormonal signals get thrown off.

•          2) Menorrhagia:

•          3) Post abortion bleeding

•          4) Post partum hemorrhages

•          5) Metrorrhagia:

•          Metrorrhagia: Uterine bleeding at irregular intervals, particularly between the expected menstrual periods. Metrorrhagia may be a sign of an underlying disorder, such as hormone imbalance, endometriosis, uterine fibroids or, less commonly, cancer of the uterus. Metrorrhagia may cause significant anemia.

•          6) IUCD (intra uterine contraceptive devices) induced menorrhagia

 

Additional Information:

• Packaging Details: 10*10 BLISTER

Product Details:

BRAND NAME-RAUF-MF TABLETS

COMPOSITION-TRANEXAMIC ACID 500 MG + MEFENAMIC ACID 250 MG TAB

PACKING-10*10 ALU-ALU TABLETS

TRANEXAMIC ACID

v  Tranexamic acid is one of the most commonly used and widely researched antifibrinolytic agents.

v  What are antifibrinolytic agents?

v  A type of drug that helps the blood clot. It prevents the breakdown of a protein called fibrin, which is the main protein in a blood clot.

v   Antifibrinolytic agents may be used to help prevent or treat serious bleeding in patients who have certain conditions, such as hemophilia, very heavy menstrual bleeding, or some types of vascular tumors. They may also be used to help prevent or control bleeding during or after surgery or after a traumatic injury.

 

VARIOUS ROLES OF TRANEXAMIC ACID

1)       Postpartum hemorrhage: is when a woman has heavy bleeding after giving birth. 

 

2) Menorrhagia: menstrual bleeding that lasts more than 7 days. It can also be bleeding that is very heavy.

 

3) Trauma-associated hemorrhage

4) Surgical bleeding

MEFENAMIC ACID

•          Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs) with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.

•          Mefenamic acid is an NSAID used to treat mild to moderate pain for no more than a week.

•          It is used for the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.

INDICATIONS OF RAUF-MF TABLETS

•          1) Dysmenorrhea:

 Dysmenorrhea the medical term for painful menstrual periods which are caused by uterine contractions. Primary dysmenorrhea refers to recurrent pain, while secondary dysmenorrhea results from reproductive system disorders. Both can be treated.

•          2) Dysfunctional uterine bleeding:

Dysfunctional uterine bleeding, also called anovulatory bleeding, is any bleeding from the vagina that varies from a woman's normal menstrual cycle. The normal cycle is triggered by signals from hormones. Dysfunctional uterine bleeding occurs when the cycle's hormonal signals get thrown off.

•          3) Menorrhagia:

•          Menorrhagia is the medical term for menstrual periods with abnormally heavy or prolonged bleeding.

•          4) Gynaecological surgeries.

 

•          5) IUD (intra uterine devices) associated menorrhagia.

Additional Information:

• Packaging Details: 10*10 BLISTER

Product Details:

BRAND NAME- VUFOL-D SOFTGELS TABLETS

COMPOSITION-DHA 200MG+ FOLIC ACID 5MG SOFT GEL CAPSULES 

PACKING-2*15 BLISTER SOFTGELS

DHA

v  Docosahexaenoic acid (DHA) is the most biologically active omega-3 fatty acid.

v  DHA have been shown to have multiple beneficial effects, including improving childhood development when ingested during pregnancy.

v  Fetal brain growth accelerates during the second half of pregnancy, and the rate of growth remains high during the first year of life with continued growth for the next several years.

v   It is likely that, during pregnancy, omega-3 requirements increase over normal to support fetal growth, particularly of the brain and eyes.

v  Deprivation of omega-3 fatty acids during
pregnancy is associated with visual and behavioral deficits that cannot be reversed with postnatal supplementation.

v   For these reasons, it is important for omega-3 fatty acids to be supplied to the fetus in adequate amounts throughout pregnancy.

v   

v  To optimize pregnancy outcomes and fetal health, consensus guidelines have recommended that pregnant women consume at least 200 mg of DHA per day. 

FOLIC ACID

v  Folate (vitamin B9) is an essential nutrient that is required for DNA replication and as a substrate for a range of enzymatic reactions involved in amino acid synthesis and vitamin metabolism.

v  Demands for folate increase during pregnancy because it is also required for growth and development of the fetus.

v   Folate deficiency has been associated with abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses (congenital abnormalities).

 

INDICATIONS OF VUFOL-D

• v  Foetus growth and development.
• v  Abnormal Foetal birth weight.
• Pre-term delivery

 

 

 

Additional Information:

• Packaging Details: 2*15 SOFTGELS PER BOX

Product Details:

BRAND NAME-ALVI VAGINAL SOFTGELS

COMPOSITION-CLINDAMYCIN 100MG+CLOTRIMAZOLE 100MG SOFT GEL CAPSULES 

PACKING- 10*1*7 BLISTER PACK SOFTGELS

•         CLINDAMYCIN

•         Clindamycin is a antibiotic, used for the treatment of numerous infections, including but not limited to septicemia, intra-abdominal infections, lower respiratory infections, gynecological infections, bone and joint infections, and skin and skin structure infections.

•         Clindamycin is also used in the treatment of streptococcal pharyngitis, acne vulgaris, bacterial vaginosis, and severe pelvic inflammatory disease.

•         Mechanism of Action of Clindamycin

•         Clindamycin prevents peptide bond formation, thereby inhibiting protein synthesis by reversibly binding to 50S ribosomal subunits.

•        CLOTRIMAZOLE

•         Clotrimazole is an  imidazole antifungal agent with broad-spectrum, antifungal activity, used primarily in the treatment of skin, oral and vaginal candida infections.

•          MECHANISM OF CLOTRIMAZOLE

•         Clotrimazole inhibits biosynthesis of sterols, particularly ergosterol, an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane.•         This results in leakage and loss of essential intracellular compounds, and eventually causes cell lysis.

•        INDICATIONS OF ALVI VAGINAL CAPSULES

•          1.CANDIDA VULVITIS

•          2.VAGINAL CANDIDIASIS

•          It is defined as symptomatic vaginitis (inflammation of the vagina), which often involves the vulva (erythema and swelling), caused by infection with a Candida yeast. The predominant symptom is vulvar itching.

•          3.VAGINAL MYCOSIS:

It is caused by a microscopic fungus – usually Candida albicans.

•          Symptoms- such as redness and significant vulvar itching, often accompanied by thick vaginal discharge.

•          4.BACTERIAL VAGINOSIS:
Bacterial vaginosis (BV) is a common vaginal infection that happens when some normal bacteria that lives in the vagina overgrows, causing a bacterial imbalance. Symptoms include an off-white or grey vaginal discharge that smells “fishy

 

 

Additional Information:

• Packaging Details: 10*1*7 softgels blister pack

Product Details:

BRAND NAME- SAPSYL-FORTE TABLETS

COMPOSITION-CRANBERRY EXTRACT 200MG + D-MANNOSE 200MG + PROBIOTICS 450 MILLION CFU + FRUCTOOLIGOSACCHRIDES 50MG + VITAMIN A 500MCG + VITAMIN C 40 MG

PACKING-3*10 TABLETS BLISTER

 CRANEBERRY EXTRACT

•         Cranberries are packed with antioxidants and other nutrients that have a ton of health benefits. 

•         Properties:

1. Antimicrobial
2. Antifungal
3. Anti-inflammatory
4. Anti-adherence
5.  used for reducing the risk of “bladder infections" (urinary tract infections).
6. Decrease smell of urine in people who are unable to control urination (incontinent)
7. also used for kidney stones, enlarged prostate, the common cold.

D-MANNOSE

•          D-mannose is a kind of sugar that is related to glucose.

•           It's found in many fruits, and also occurs naturally in the human body.

•           D-mannose might also prevent certain kinds of bacteria from sticking to the walls of the urinary tract and causing infection.

•           D-mannose might work to treat or prevent a UTI by stopping E.coli bacteria from latching on.

•          D-mannose is typically used for preventing a UTI in people who have frequent UTIs or for treating an active UTI

PROBIOTICS

•          The use of probiotics, especially lactobacilli, has been considered for the prevention of UTIs. 

•          restoration of the urogenital flora, which is dominated by uropathogens, with lactobacilli may protect against UTIs.

FRUCTOOLIGOSACCHRIDES

•          induce higher growth of gut flora.

 

•          improve moisture retention

•          maintain healthy gut microbiota 

VITAMIN A

•          Vitamin A has been called the anti-infection vitamin because of its role in helping the body fight bacterial, parasitic, and viral infections.

•          Vitamin A supplementation may have an adjuvant effect on the treatment of RUTI.(recurrent lower urinary tract infections )

VITAMIN C

•          Vitamin C, also called “ascorbic acid,” is believed to create an acidic environment, triggering the production of nitric oxide, and thereby causing the bacteria present to end their own existence.

INDICATIONS OF SAPSYL- FORTE TABLETS

RECURRENT UTI INFECTIONS

Additional Information:

• Packaging Details: 3*10 BLISTER PACKING TABLETS

Product Details:

NATURAL PROGESTERONE 200MG SUSTAIN RELEASED is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance.

Product Details:

BRAND NAME-ALNASTER-5 TABLET

COMPOSITION: ALLYLESTRENOL 5 MG TAB

PACKING- 10*10 BLISTER PACK

Allylestrenol

•         Allylestrenol is  synthetic progestogen structurally related to progesterone.

•         It has an interesting pharmacological profile,  combining potent pregnancy-maintaining and fetal weight-promoting properties,

•         WHY TO CHOOSE ALLYLESTRENOL THAN OTHER PROGESTINS AVAILABLE?

•         Allylestrenol is completely free  from androgenic activity as well as  well tolerated in comparison to other progestins.

•         Allylestrenol in this respect, by  not having any androgenic activity, has no teratological  effects.

•          It has no  known endocrinological side effects and thus, it is perfectly  devoid of androgenic, estrogenic, and anabolic properties.

INDICATIONS OF ALNASTER-5 TABLETS

•         1) Miscarriage (Threatened and Recurrent  Miscarriage)

•         2) Intrauterine Growth Restriction/Fetal Growth  Restriction/Small for  Gestational Age

•         3) Threatened Preterm Labor

•         4) Pregnancy-induced Hypertension

•         5) selected cases of bad obstetric history (habitual abortion)

Additional Information:

• Packaging Details: 10*10 BLISTER TABLETS

Product Details:

BRAND NAME- WISENOR- CR TABLETS

COMPOSITION-NORTHINDRONE ACETATE USP 10 MG (NORTHISTERONE 10MG) 

PACKING - 10*10 ALU-ALU TABLETS

NORTHISTERONE/NORTHINDRONE

•         man-made form of progesterone (a naturally occurring female sex hormone).

•          At low dose (≤1 mg a day) it can be use in combination with estrogens either as a contraceptive or in hormone replacement therapy. 

•         At higher dose (≥5 mg daily) it can be used for menorrhagia, to treat metropathia haemorrhagica, and to postpone menstruation.

 

Why Northisterone is superior alternative to oral contraceptives?

•         Delay menstruation without causing spotting.

•         well tolerated.

•         Unlike contraceptives, norethindrone allows for an immediate return to fertility after discontinuation.

•         Norethindrone has minimal pro-coagulant effects, making it an excellent choice in patients at risk for VTE or cardiovascular disease.

•         Ovulation blocking effect 11 to 25 times more potent than levonorgestrel and medroxyprogesterone acetate respectively. 

•         at clinical doses, norethisterone has hardly any androgenic effect.  

•         Safer long-term use with minimal toxic effect.

 INDICATIONS-
1) Endometyriosis
2) Secondary amenorrhea
3) Abnormal uterine bleeding due to hormonal imbalance 
4) PMS

Additional Information:

• Packaging Details: 10*10 ALU ALU

Product Details:

BRAND NAME-CAGPRO-0.5 TABLETS

COMPOSITION-Cabergoline 0.5 mg 

PACKING- 10*1*4 STRIP PACKING TABLETS

CABERGOLINE

v Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor.

v It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome.

v  Cabergoline possesses potent agonist activity on dopamine D2 receptors.

 

MECHANISM OF CABERGOLINE

It acts by direct stimulation of the D2-dopamine receptors on pituitary lactotrophs, thus inhibiting  prolactin 

INDICATIONS-
TREATMENT OF HYPERPROLACTINEMIC DISORDERS DUE TO IDIOPATHIC AND PITUITARY ADENOMAS

* INHIBITION AND SUPPRESSION OF PHYSIOLOGICAL LACTATION IN BELOW CASES-
1) After stillbirth or abortion
2) When breast feeding is contraindicated due to medical reasons related to the mother or newborn

Additional Information:

• Packaging Details: 10*1*4 STRIP PACK

Product Details:

BRAND NAME- WISEFEO-500 INJECTION

COMPOSITION- HYDROXYPROGESTERONE CAPROATE 500 MG

PACKING- 2ML/DISPOSABLE 

•          HYDROXYPROGESTRONE

•         Hydroxyprogesterone caproate injection is a prescription hormone medicine (progestin) used in women who are pregnant and who have delivered a baby too early (preterm) in the past.

•         Hydroxyprogesterone caproate injection is used in these women to help lower the risk of having a preterm baby again.

•         Hydroxyprogesterone is a synthetic,potent, long-acting, progestational steroid ester which transforms proliferative endothelium into  secretory endothelium, induces mammary gland duct development, and inhibits the production and/or release of gonadotropic hormone; it also shows slight estrogenic, androgenic, or corticoid effects as well, but should not be relied upon for these effects.

INDICATION-

•  •          1.Amenorrhea:

  •          Amenorrhea (uh-men-o-REE-uh) is the absence of menstruation, often defined as missing one or more menstrual periods.

  •          Primary amenorrhea refers to the absence of menstruation in someone who has not had a period by age 15. The most common causes of primary amenorrhea relate to hormone levels, although anatomical problems also can cause amenorrhea.

  •          Secondary amenorrhea refers to the absence of three or more periods in a row by someone who has had periods in the past. Pregnancy is the most common cause of secondary amenorrhea, although problems with hormones also can cause secondary amenorrhea.

  2.Prevention of preterm labour:

  v Preterm labor occurs when regular contractions result in the opening of your cervix after week 20 and before week 37 of pregnancy. Preterm labor can result in premature birth. The earlier premature birth happens, the greater the health risks for your baby.

  3.Dysfunctional uterine bleeding (DUB):

  v Dysfunctional uterine bleeding occurs when the normal cycle of menstruation is disrupted, usually due to anovulation (failure to ovulate) that's unrelated to another illness. Ovulation failure is the most common type of DUB in adolescents and in women who are reaching perimenopause.

  4.Advanced uterine cancer:

  v The significance of progesterone in controlling estrogen-driven proliferation is underlined by its efficacy in preventing endometrial cancer. Progestins are used in the clinic effectively to eradicate some but not all endometrial hyperplasia and well-differentiated endometrioid endometrial cancer.

Additional Information:

• Packaging Details: 2 ML DISPOPACK

Product Details:

BRAND NAME- DOUCH VAGINAL WASH 

COMPOSITION-LACTIC ACID 1.2% W/V+ TRICLOSAN 0.3% W/V + ALOE VERA 3% W/V + TEA TREE OIL 0.05% W/V + COCAMIDOPROPYL BETAINE 7.0% W/V + POLYQUATERMINE- 0.5%W/V + HIPPOPHEA RAHMNOIDES 0.025% W/V

PACKING-100 ML 

 LACTIC ACID

It isa  key natural antimicrobial ingredient that correlates with vulvovaginal health, as lactic acid helps maintain an acidic pH in the vulvovaginal area to augment skin homeostasis and prevent the growth of harmful bacteria.

TRICLOSAN
Triclosan is an antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew.

 At lower concentrations, however, triclosan appears bacteriostatic and is seen to target bacteria mainly by inhibiting fatty acid synthesis. Triclosan binds to enoyl-acyl carrier protein reductase enzyme (ENR).

This complex has increased affinity for NAD+ and forms a ternary complex.

This complex is unable to participate in fatty acid synthesis, weakening the cell membrane and causing cell death.

Humans do not have an ENR enzyme, and thus are not affected.

ALOE VERA

Aloe vera contains antifungal properties that are beneficial for reducing the symptoms of vaginal infections.

Aloe vera gel can soothe dry and inflamed skin around the vaginal area.

The gel can also help reduce itching and burning associated with vaginal infection.

TEA TREE OIL

Tea tree oil is an essential oil that's used to kill fungi, bacteria, and viruses.

 Research suggests that a vaginal suppository containing tea tree oil may help treat vaginal infections.

Tea tree oil has been shown to have antifungal properties.

Additional Information:

• Packaging Details: 100 ml bottle

Product Details:

BRAND NAME- WISEFEO-250 INJECTION

COMPOSITION- HYDROXYPROGESTERONE CAPROATE 250 MG

PACKING- 1ML/DISPOSABLE 

•          HYDROXYPROGESTRONE

•         Hydroxyprogesterone caproate injection is a prescription hormone medicine (progestin) used in women who are pregnant and who have delivered a baby too early (preterm) in the past.

•         Hydroxyprogesterone caproate injection is used in these women to help lower the risk of having a preterm baby again.

•         Hydroxyprogesterone is a synthetic,potent, long-acting, progestational steroid ester which transforms proliferative endothelium into  secretory endothelium, induces mammary gland duct development, and inhibits the production and/or release of gonadotropic hormone; it also shows slight estrogenic, androgenic, or corticoid effects as well, but should not be relied upon for these effects.

INDICATION-

•  •          1.Amenorrhea:

  •          Amenorrhea (uh-men-o-REE-uh) is the absence of menstruation, often defined as missing one or more menstrual periods.

  •          Primary amenorrhea refers to the absence of menstruation in someone who has not had a period by age 15. The most common causes of primary amenorrhea relate to hormone levels, although anatomical problems also can cause amenorrhea.

  •          Secondary amenorrhea refers to the absence of three or more periods in a row by someone who has had periods in the past. Pregnancy is the most common cause of secondary amenorrhea, although problems with hormones also can cause secondary amenorrhea.

  2.Prevention of preterm labour:

  v Preterm labor occurs when regular contractions result in the opening of your cervix after week 20 and before week 37 of pregnancy. Preterm labor can result in premature birth. The earlier premature birth happens, the greater the health risks for your baby.

  3.Dysfunctional uterine bleeding (DUB):

  v Dysfunctional uterine bleeding occurs when the normal cycle of menstruation is disrupted, usually due to anovulation (failure to ovulate) that's unrelated to another illness. Ovulation failure is the most common type of DUB in adolescents and in women who are reaching perimenopause.

  4.Advanced uterine cancer:

  v The significance of progesterone in controlling estrogen-driven proliferation is underlined by its efficacy in preventing endometrial cancer. Progestins are used in the clinic effectively to eradicate some but not all endometrial hyperplasia and well-differentiated endometrioid endometrial cancer.

Additional Information:

• Packaging Details: 1ML DISPO PACK

Product Details:

BRAND NAME-DUDOT-AC TABLETS

COMPOSITION-DROTAVERINE 80 MG + ACECLOFENAC 100 MG

PACKING-10*10 ALU-ALU PACKING TABLETS

•         DROTAVERINE

•         Drotaverine is an antispasmodic drug with a relaxing effect on smooth muscles.

•         structurally related to papaverine, although it displays more potent antispasmodic activities than papaverine.

•         INDICATIONS ARE:

•          used to alleviate gastrointestinal and genitourinary smooth muscle     spasms, such as   cholecystitis (inflammation of the gall  bladder) and gallbladder disorders.

•         ACECLOFENAC

•         Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

•         Aceclofenac is also reported to be  effective in other painful conditions
 such as dental and gynaecological conditions.

INDICATIONS-

-primary dysmenorrhea 
-abdominal pain
-bloating, 
-discomfort and cramps
-irritablebowel syndrome (IBS)
-Muscle spasm or contractions in stomach and gut 

Additional Information:

• Packaging Details: 10*10 ALU-ALU PACK tablets

Product Details:

 BRAND NAME-DINOWISE TABLETS

COMPOSITION- DIENOGEST 2 MG

PACKING- 10*10 ALU-ALU PACKING TABLETS

•           DIENOGEST

•         Dienogest is an orally-active semisynthetic progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.

•         Dienogest exhibits a very potent progestagenic effect in the endometrium, and causes endometrial atrophy after prolonged use  .

•         It also mediates an antiandrogenic effect that is equivalent to approximately one third that of cyproterone acetate.

             It is an antagonist at androgen 

INDICATIONS-
 1) Pelvic pain associated with endometriosis
.Endometriosis: an often painful disorder in which tissue similar to the tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus. Endometriosis most commonly involves your ovaries, fallopian tubes and the tissue lining your pelvis.
2. contraception in combination with ethinylestradiol

Common signs and symptoms of endometriosis include:

 

•         Painful periods (dysmenorrhea). Pelvic pain and cramping may begin before and extend several days into a menstrual period. You may also have lower back and abdominal pain.

•         Pain with intercourse. Pain during or after sex is common with endometriosis.

•         Pain with bowel movements or urination. You’re most likely to experience these symptoms during a menstrual period.

•         Excessive bleeding. You may experience occasional heavy menstrual periods or bleeding between periods (intermenstrual bleeding).

 

•         Infertility. Sometimes, endometriosis is first diagnosed in those seeking treatment for infertility.

Additional Information:

• Packaging Details: 10*10 ALU ALU PACK TABLETS

Product Details:

BRAND NAME- SINUCAL PLUS SOFTGELS

COMPOSITION-CORAL CALCIUM 225MG+FOLIC ACID 1.5MG+VITAMIN B6 3MG+METHYLCOBALAMIN 1500MCG+VITAMIN 200IU

PACKING-10*1*10 BLISTER SOFTGELS

•          CALCIUM CARBONATE (CORAL GRAINS)

•         Coral calcium is a supplement usually derived from coral sand deposits.

•         These sand deposits, which were once part of a coral reef, are typically collected directly from coastal land or shallow waters surrounding it.

•         Coral calcium supplements are comprised largely of calcium carbonate but may also contain small amounts of magnesium and other trace minerals.

•         BENEFITS OF CORAL CALCIUM

•         It’s less dense than calcium carbonate from limestone, and absorbs quickly into your bloodstream.

•          It’s easier for your stomach to handle.

•         It has greater surface area: because of all the holes, one gram of coral calcium is larger than one gram of other types of calcium carbonate. This means that gram for gram, more calcium is exposed to and absorbed by the cells in your body.

•         It has high bioavailability: high absorption means more calcium reaches your system, and less leaves your body as waste. So you get the coral calcium benefits: sango calcium, magnesium and various other coral minerals you need.
•         FOLIC ACID

•         Folate (vitamin B₉) is an essential nutrient that is required for  DNA replication and as a substrate for a range of enzymatic reactions involved  in amino acid synthesis and vitamin metabolism.

•         Demands for folate increase during pregnancy because it is also required for  growth and development of the fetus. Folate deficiency has been associated with  abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses
(congenital abnormalities).

•         Dietary supplementation with folic acid around the time of conception has  long been known to reduce the risk of neural tube defects (NTDs) in the  offspring.

INDICATIONS-
1) Senile osteoporosis
2) Drug induced osteoporosis
3) Post menopauseal osteoporosis
4) Pregnancy and lactation
5) prevention of osteopenia

Additional Information:

• Packaging Details: 10*1*10 BLISTER

Product Details:

BRAND NAME- WOOCARE UTERINE TONIC

COMPOSITION- AYURVEDIC UTERINE TONIC

PACKING-200 ML BOTTLE 

•      Saraca indica  (Ashoka)  

•      Ashoka : Ashoka has been traditionally used in Indian Ayurveda as a uterine tonic and has been indicated in menstrual irregularities in DUB (Dysfunctional uterine Bleeding).

•       Ashoka helps to controlling uterine fibroid bleeding & leucorrhoea because of steroids.

•      The herb benefits the endometrium and uterine muscles and this makes it effective as a uterine tonic for irregular menstrual cycles. It is so effective in all types of abnormal discharges per vagina.

Asparagus racemosus   (Satavri) 

 •         Shatavari is recommended in the Ayurveda for the prevention and treatment of reproductive disorders of women such as sexual debility, ammenorrhea, dysmenorrhea, dysfunctional uterine bleedingendometriosis, gonorrhea, prolapse of uterus.

•         Shatavari has Shatavarin I-IV Saponins which restores hormonal balance in women with fluctuating hormonal levels due to menstruation & menupause.

•         It moistens dry tissues of the sexual organs, enhances folliculogenesis and ovulation .

Woodifordia floribunda  (Dhataki)  

•         •         Dhataki flowers are astringent & analgesic and used for preparing various medicines in ayurvedic medicine system. In Ayurvedic scriptures  this herb possesses various properties like Paradara (menstrual disorders), Garabhasthapaka (fertility agent), control Atisara (Anti diarrheal) & Visha (Poisoning).

Withania somnifera (Ashwgandha) 180mg

•         It has been used with benefit against fibroid uterine tumors.

•         Ashwagandha has Anaferine Alkaloids because of which it act as relaxant and antispasmodic effects against several spasmogens on uterine muscles.

•         Aroma Coffee (Abroma augusta) It regulates the menstrual flow and also used as anti-fertility agent.

INDICATIONS-

 1) Leucorrhoea
It is a medical condition where women experiences thick whitish or yellowish colour discharge from the vagina which is mainly experienced during puberty, when sexual organs are developing in a woman.

2) Menorrhagia
Menorrhagia is the medical term for menstrual periods with abnormally heavy or prolonged bleeding.

 3) Metrorrhagia
Uterine bleeding at irregular intervals, particularly between the expected menstrual periods. Metrorrhagia may be a sign of an underlying disorder, such as hormone imbalance, endometriosis, uterine fibroids or, less commonly, cancer of the uterus. Metrorrhagia may cause significant anemia.

4) Strengthen the uterus

5) Improves ovarian function & reproductive health.

6) Supports the female hormonal system.

 

Additional Information:

• Packaging Details: 200 ml bottle

Product Details:

BRAND NAME- SAPSYL-XT TABLETS

COMPOSITION- FERROUS ASCORBATE 100MG + FOLIC ACID 1.5MG + ZINC 22.5MG.

PACKING-10*10 STRIP TABLETS

ü  Ferrous ascorbate is a medication used to treat iron-deficiency anemia.

ü  The major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.

ü  Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.

ü Folate (vitamin B9) is an essential nutrient that is required for  DNA replication and as a substrate for a range of enzymatic reactions involved  in amino acid synthesis and vitamin metabolism.

ü  Demands for folate increase during pregnancy because it is also required for  growth and development of the fetus. Folate deficiency has been associated with  abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses
(congenital abnormalities).

 

ü  Dietary supplementation with folic acid around the time of conception has  long been known to reduce the risk of neural tube defects (NTDs) in the offspring.

INDICATIONS-
 ü  Pregnancy related anaemia.

ü  Iron deficiency anaemia.

ü  Post-surgical blood loss.

ü  Chronic blood loss.

Additional Information:

• Packaging Details: 10*10 STRIP PACKING

Product Details:

BRAND NAME- SAPSYL-XT SYRUP

COMPOSITION- FERROUS ASCORBATE 30MG + ELEMENTAL FOLIC ACID 550MCG

PACKING-200 ML  SYRUP 

Ferrous ascorbate is a medication used to treat iron-deficiency anemia.

The major activity of supplemental iron is in the prevention and treatment of iron deficiency anemia. Iron has putative immune-enhancing, anticarcinogenic and cognition-enhancing activities.

 Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia.

Folate (vitamin B9) is an essential nutrient that is required for  DNA replication and as a substrate for a range of enzymatic reactions involved  in amino acid synthesis and vitamin metabolism.

Demands for folate increase during pregnancy because it is also required for  growth and development of the fetus. Folate deficiency has been associated with  abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses
(congenital abnormalities).

 Dietary supplementation with folic acid around the time of conception has  long been known to reduce the risk of neural tube defects (NTDs) in the offspring.

INDICATIONS-

•  Pregnancy related anaemia.
•  Iron deficiency anaemia.
•  Post-surgical blood loss.
•  Chronic blood loss.

Additional Information:

• Packaging Details: 200 ML

Product Details:

BRAND NAME- SAPSYL-FE TABLETS

COMPOSITION-FEROUS BIS GLYCINATE 60MG+ FOLIC ACID IP 1MG+ ZINC BIS GLYCINATE 15MG + METHYLCOBALAMIN 500 MCG

PACKING-10*10 BLISTER

FEROUS BIS GLYCINATE

•         Ferrous bisglycinate is a chelate that is used as a source of dietary iron.

•         It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

FOLIC ACID

•         Folate (vitamin B₉) is an essential nutrient that is required for DNA replication and as a substrate for a range of enzymatic reactions involved in amino acid synthesis and vitamin metabolism.

•         Demands for folate increase during pregnancy because it is also required for growth and development of the fetus. Folate deficiency has been associated with abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses (congenital abnormalities).

•         Dietary supplementation with folic acid around the time of conception has long been known to reduce the risk of neural tube defects (NTDs) in the offspring.

ZINC BIS GLYCINATE

•         Poor maternal zinc status has been associated with foetal loss, congenital malformations, intrauterine growth retardation, reduced birth weight, prolonged labour and preterm or post-term deliveries.

•         Zinc plays an important role in many biological functions including protein synthesis, cellular division and nucleic acid metabolism

INDICATIONS OF SAPSYL-FE TABLETS

•         1.Iron Deficiency Anaemia

 

•         2. Megaloblastic Anaemia

 

 

Additional Information:

• Packaging Details: 10*10 BLISTER

Product Details:

 BRAND NAME-SAPSYL-HB TABLETS

COMPOSITION-FERRIUS ASPRATO GLYCINATE 100MG+L-METHYLFOLATE CALCIUM 300MCG + METHYLECOBALAMIN 500MCG

PACKING- 10*1*10

   FERROUS ASPRATO GLYCINATE

•      Ferrous asparto glycinate is an iron-amino acid chelate. It is available as a dietary supplement used in the treatment of iron deficiency and iron deficiency anemia. 

•      Ferrous asparto glycinate is an effective iron-amino acid chelate in the management of iron deficiency anaemia (IDA) in pregnant women as compared with ferrous ascorbate.

•      Significantly higher levels of haemoglobin and ferritin with ferrous asparto glycinate treatment as compared with ferrous ascorbate.

L-METHYLFOLATE CALCIUM

•      Calcium L-methylfolate is a source of folate and an alternative to folic  acid for use in human food and food supplements.

•      Maintaining an adequate folate status is particularly important during  periods of rapid cell proliferation and tissue growth such as gestation and  infancy. Folate deficiency has been associated with increased risk for neural  tube defects, certain chronic diseases and cancer.

METHYLCOBALAMIN

•      Vitamin B6 and vitamin B12 have significant roles in homocysteine (Hcy) regulation. In the pathophysiology of PCOS, a positive correlation has been reported between IR and elevated Hcy levels.

•      Kaya et al. demonstrated that IR, obesity, and increased Hcy levels were related to low serum insulin B12 concentrations in women with PCOS. In order to reduce elevated levels of serum Hcy, folic acid supplementation for 3 months produced effective results, especially in women without insulin resistance.

•      Metformin inhibits the binding intrinsic factor–B12 complex and its receptor, and also serum vitamin B12 and folic acid levels
decrease during metformin therapy. Metformin increases Hcy levels. Supplements of vitamins had no effects on androgen and
lipid levels in the pathophysiology of PCOS.

•      INDICATIONS OF SAPSYL-HB

•      Iron deficiency anaemia.

•      Pregnancy and lactation.

•      Chronic blood loss.

•      Chronic illness

Product Details:

BRAND-NAME- FEOFER-OVA COMBIKIT

COMPOSITION--Each kit having EACH TABLET CONTAINS : CLOMIPHENE CITRATE  50MG + N-ACETYLECYSTEINE 600MG  EACH CAPSULES CONTAINS : ASTAXANTHIN 4MG    

PACKING- KIT OF 5 TABLETS + 25 CAPS

CLOMIPHENE CITRATE

v  Clomiphene citrate is the treatment of first choice in the management of infertility in normally oestrogenized, anovulatory women (WHO group II). 
v   In order to increase pregnancy  rate, couples with infertility of  unknown origin can undergo ovulation induction and

 

        intrauterine insemination.

v   Clomiphene citrate and menopausal or recombinant gonodotropins  are the most used drugs to induce ovulation.

 

N-ACETYLECYSTEINE (NAC)

•          NAC is a safe and well-tolerated adjuvant to clomiphene citrate for induction of ovulation can improve the ovulation and pregnancy rates in PCOS patients. It may also have some beneficial impacts on endometrial thickness.

•          NAC can be an effective adjuvant in PCOS related and unexplained female infertility.

ASTAXANTHIN

ü  Astaxanthin is an antioxidant.

ü  This effect might protect cells from damage.

ü   Astaxanthin might also improve the way the  immune system functions.

INDICATIONS OF FEOFER-OVA COMBIKIT

q  For treating female infertility resulting from:

1. Ovulatory dysfunction:

When a woman has irregular, infrequent (less than nine per year) menstrual periods or does not ovulate at all, she is said to have ovulatory dysfunction. Normally, one ovary releases an egg each month, which may be fertilized if it comes into contact with sperm.

A woman with ovulatory dysfunction does not release an egg each month.

•          The main symptoms of ovulatory dysfunction are:Sporadic, irregular periods

•          Inability to get pregnant (infertility)

2.Poly cystic ovary syndrome (PCOS): is a hormonal disorder common among women of reproductive age. Women with PCOS may have infrequent or prolonged menstrual periods or excess male hormone (androgen) levels. The ovaries may develop numerous small collections of fluid (follicles) and fail to regularly release eggs.

   3.Amenorrhea-galactorrhoea syndrome:

•             Rare endocrine disorder that affects women who have recently given birth (postpartum) and is characterized by the over-production of breast milk (galactorrhea), lack of ovulation (anovulation), and the absence of regular menstrual periods (amenorrhea).

•          4.Psychogenic amenorrhea: functional hypothalamic amenorrhea or stress-related amenorrhea when the condition is viewed only in relation to altered neuroendocrine function or to its etiopathogenesis.

 

Additional Information:

• Packaging Details: KIT OF 5 TABLETS + 25 CAPS

Product Details:

BRAND-NAME- FEOFER-OVA DS COMBIKIT

COMPOSITION-Each kit having EACH TABLET CONTAINS : CLOMIPHENE CITRATE  100MG + N-ACETYLECYSTEINE 600MG  EACH CAPSULES CONTAINS : ASTAXANTHIN 4MG  

PACKING- KIT OF 5 TABLETS + 25 CAPS

CLOMIPHENE CITRATE

v  Clomiphene citrate is the treatment of first choice in the management of infertility in normally oestrogenized, anovulatory women (WHO group II). 
v   In order to increase pregnancy  rate, couples with infertility of  unknown origin can undergo ovulation induction and

 

        intrauterine insemination.

v   Clomiphene citrate and menopausal or recombinant gonodotropins  are the most used drugs to induce ovulation.

 

N-ACETYLECYSTEINE (NAC)

•          NAC is a safe and well-tolerated adjuvant to clomiphene citrate for induction of ovulation can improve the ovulation and pregnancy rates in PCOS patients. It may also have some beneficial impacts on endometrial thickness.

•          NAC can be an effective adjuvant in PCOS related and unexplained female infertility.

ASTAXANTHIN

ü  Astaxanthin is an antioxidant.

ü  This effect might protect cells from damage.

ü   Astaxanthin might also improve the way the  immune system functions.

INDICATIONS OF FEOFER-OVA COMBIKIT

q  For treating female infertility resulting from:

1. Ovulatory dysfunction:

When a woman has irregular, infrequent (less than nine per year) menstrual periods or does not ovulate at all, she is said to have ovulatory dysfunction. Normally, one ovary releases an egg each month, which may be fertilized if it comes into contact with sperm.

A woman with ovulatory dysfunction does not release an egg each month.

•          The main symptoms of ovulatory dysfunction are:Sporadic, irregular periods

•          Inability to get pregnant (infertility)

2.Poly cystic ovary syndrome (PCOS): is a hormonal disorder common among women of reproductive age. Women with PCOS may have infrequent or prolonged menstrual periods or excess male hormone (androgen) levels. The ovaries may develop numerous small collections of fluid (follicles) and fail to regularly release eggs.

   3.Amenorrhea-galactorrhoea syndrome:

•             Rare endocrine disorder that affects women who have recently given birth (postpartum) and is characterized by the over-production of breast milk (galactorrhea), lack of ovulation (anovulation), and the absence of regular menstrual periods (amenorrhea).

•          4.Psychogenic amenorrhea: functional hypothalamic amenorrhea or stress-related amenorrhea when the condition is viewed only in relation to altered neuroendocrine function or to its etiopathogenesis.

 

Additional Information:

• Packaging Details: KIT OF 5 TABLETS + 25 CAPS

Product Details:

BRAND NAME-VOMYFLO TABLETS

COMPOSITION-DOXYLAMINE 10MG + PYRIDOXINE 10MG + FOLIC ACID 2.5MG TABLETS 

PACKING-10*10 ALU-ALU TABLETS

 DOXYLAMINE

ü  Doxylamine is an antihistamine used to treat insomnia and allergy symptoms and is used with pyridoxine in the treatment of nausea and vomiting in pregnancy.

ü  MECHANISM OF DOXYLAMINE

ü  Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects.

PYRIDOXINE (VITAMIN B6)

ü  Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods.

ü  As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body.

ü  Pyridoxine is a vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy in a combination         product with Doxylamine.

FOLIC ACID (VITAMIN B9)

ü  Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis.

ü  Folic acid is particularly important during phases of rapid cell division, such as infancy, pregnancy, and erythropoiesis, and plays a protective factor in the development of cancer.

ü  Inadequate folate levels can result in a number of health concerns including cardiovascular disease, megaloblastic anemias, cognitive deficiencies, and neural tube defects (NTDs).

INDICATION OF VOMYFLO TABLET

ü  It is used to treat Morning sickness (nausea and vomiting during pregnancy): It usually begins in the 6th week of pregnancy        lasting up to 16 to 18 weeks.

ü  However, some pregnant women have it throughout pregnancy. It can lead to electrolyte imbalances
 and weight loss in pregnant  women.

Additional Information:

• Packaging Details: 10*10 blister packing tablets

Product Details:

BRAND NAME-VUFOL-FORTE SOFTGELS

COMPOSITION-L-METHYL FOLATE 800MCG + DHA 200MG + VITAMIN D3  1000 I.U. SOFT GEL CAPSULES 

PACKING-2*15 SOFTGELS BLISTER PACK

L-METHYL FOLATE

•        L-METHYLFOLATE belongs to a class of medications called ‘Nutritional supplements’ primarily used to treat low red blood cells level due to various complications or long term disease. 

•        It is used to prevent and treat the low levels of folic acid in the blood during certain health conditions (anaemia, pregnancy, inadequate diet, surgery recovery).

•        Deficiencies of dietary folic acid can lead to abnormalities in the mother (anemia, peripheral neuropathy) and the fetus (congenital abnormalities).

DHA
v  DHA have been shown to have multiple beneficial effects, including improving childhood development when ingested during pregnancy.

v  Deprivation of omega-3 fatty acids during pregnancy is associated with visual and behavioral deficits that cannot be reversed with postnatal supplementation.

v  To optimize pregnancy outcomes and fetal health, consensus guidelines have recommended that pregnant women consume at least 200 mg of DHA per day.

VITAMIN D3

v  Maternal vitamin D insufficiency during pregnancy is a common issue and a significant public health problem at the global level.

v  With severe maternal vitamin D deficiency, the fetus may rarely develop neonatal seizures due to hypocalcemia or rickets in utero that is manifested at birth.

v  Studies conducted in the 1980s showed that profound vitamin D deficiency was associated with impaired fetal growth

INDICATIONS OF VUFOL FORTE

v  1) Pre-eclampsia:

v  Preeclampsia is a complication of pregnancy. With preeclampsia, you might have high blood pressure, high levels of protein in urine that indicate kidney damage (proteinuria), or other signs of organ damage. Preeclampsia usually begins after 20 weeks of pregnancy in women whose blood pressure had previously been in the standard range.

v  Left untreated, preeclampsia can lead to serious — even fatal — complications for both the mother and baby.

v  2) Neural Birth defects: that occur in the development of the spinal cord and brain of some babies. The most common defects are spina bifida (abnormal development of part of the spine and spinal cord) and anencephaly (severely abnormal development of the brain).

v  About 2 in 3 neural tube defects can be prevented through increasing folate (folic acid) intake at least a month before pregnancy and during the first 3 months of pregnancy.

v  3) Preterm Birth/premature birth:
v   — delivery before 37 weeks.

v  So the patients having history of preterm birth should be prescribed with Vufol-Forte for a healthy baby during birth.

v  4.Intra-Uterine growth retardation.

v  Intrauterine growth restriction, or IUGR, is when a baby in the womb (a fetus) does not grow as expected.

 

Additional Information:

• Packaging Details: 2*15 SOFTGELS

Product Details:

This combination hormone medication is used to prevent pregnancy. It contains 2 hormones: dienogest (a progestin) and estradiol valerate (an estrogen). It works mainly by preventing the release of an egg (ovulation) during your menstrual cycle.